Endocrine Abstracts

Objective: Resveratrol is a phytoestrogen with various antiproliferatic and proapoptotic effects. One of the underlying mechanisms is downregulation of apoptosis inhibitors, such as Survivin. In human pituitary adenoma cells, Survivin expression is increased as compared to healthy pituitary gland tissue. This in vitro study aims to analyze the effect of Resveratrol on GH3 pituitary adenoma cells of the rat.Methods: GH3 cells were cultivated in F-1...